Pharmacogenomics (PGx)

Pharmacogenomics made simple for everyone

MHS Labs Pharmacogenomics is a testing and analytics service to help pharmacists and physicians prescribe accurately targeted drug therapies. Our lab analysis with clinical medication decision support provides a lifetime benefit that follows the patient throughout the continuum of care. With our pharmacogenomic insights, care networks can:

  • Personalize and optimize patient outcomes
  • Predict and monitor drug efficacy
  • Prevent adverse drug reactions (Gene-Drug and Drug-Drug)
  • Reduce Time, Costs and Errors

Mental Health 

12.7% of the U.S. population over age 12 took antidepressant medication in the past month and 50% of patients do not adequately respond.

Cardiovascular Health

Many severe adverse effects are related to a popular blood thinner.
Major bleeding and thrombosis risk can be reduced or eliminated with the proper medication.

Nursing Homes

More than half of NH residents genotyped had major or moderate PGx interactions with “at-risk” medications including commonly prescribed drugs in older adults.

Pharmacogenomics (PGx)

Will this drug work for me?

Depending on your genetic makeup, some drugs may work more effectively for you than they do in other people. Likewise, some drugs may produce more or fewer side effects in you than in someone else.

Pharmacogenomics uses information about a person’s genetic makeup to choose medications and medication doses that are likely to work best for that person. Until recently, drugs have been developed with the idea that each drug works generally the same in everybody. However, genomic research has changed the one size fits all approach.

Pharmacogenomics is personalized medicine and the future of patient care

Personalized medicine is the tailoring of medical treatment to the individual characteristics of each patient. This approach relies on scientific breakthroughs in our understanding of how a person’s unique molecular and genetic profile makes them susceptible to certain diseases.

Information about your genetic makeup can assist your doctor in prescribing medicines that are most likely to work for you. This helps your doctor avoid the trial-and-error approach of trying various medications unlikely to work for you until finding the right one.

This test may also help your physician make critical adjustments to the dosages of certain medications, as well as avoid prescribing combinations of medications that may cause you to experience an adverse drug reaction.

Understanding how you metabolize the medications that you are prescribed allows you and your doctor to customize your treatment and determine the safest, most effective dose for you. Personalized medicine provides your physician with tools to predict which medical treatments will be safe and effective for you, and which ones will not be.

How does the test work?

If you choose to be tested, a buccal or cheek swab, or a blood sample is collected and sent to our lab for testing. Once we receive the sample, we will test your DNA to determine your body’s response to medications. Results are then sent to your physician and pharmacist.

What do the results tell you?

Results from your Pharmacogenomics testing will provide information on how quickly your body metabolizes or filters a given drug. Some people are rapid metabolizers. They flush drugs quickly from their system and may not realize any benefit from taking a normal or one-size-fits-all dose.

A person who is a slow metabolizer is just the opposite. In a person who is a slow metabolizer, a normal dose of medication can build up to potentially dangerous levels.

MHS Labs Pharmacogenomics (PGx) gene test includes the following genes:










Factor II

Factor V Leiden